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Spices have been eaten for millennia. Turmeric and chilli, in particular, have been researched extensively in recent decades. And while consuming them is correlated with some health benefits, those benefits – and the reasons for them – are not what you might think.

Spices have been a part of our diets for thousands of years – it’s second nature to sprinkle our chips with pepper, sip on ginger tea and add chillies to our meals. But recently, some spices have been unofficially promoted from everyday culinary staples to all-healing superfoods.

Hillary Clinton reportedly ate one chilli pepper a day while on the campaign trail in an attempt to ward off illness. Turmeric, which has been used in Asia for millennia, recently has found its way into coffee shops around the world in the form of “golden lattes” – and, most recently, into viral messages that claim it can “boost your immune system” and protect you from getting sick. Meanwhile, cayenne pepper still hasn’t recovered since the ill-advised “Beyoncé diet” back in 2013, which suggested consuming a concoction of cayenne pepper, maple syrup, lemon and water to lose weight. (Also see our story on whether “boosting” your immune system can really protect you).

But do spices really add any health benefits to our food, or help us ward off illness? And can any of them actually do us harm?

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One of the most well known and widely used spices are chilli peppers. Many studies have examined their potential effects on our health – but have found both beneficial and adverse results.

Many studies have looked at how chilli peppers can affect our health, but results are mixed (Credit: Getty Images)

Capsaicin is the main active ingredient in chillies. When we eat chillies, capsaicin molecules interact with the temperature receptors in our bodies, sending signals to the brain to create the feeling of heat.

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Some studies point to the idea that capsaicin may help you live longer.

In 2019, an Italian study found that people who ate food seasoned with chilli peppers four times a week had a lower risk of death compared to those who never ate chillies. (Researchers controlled for lifestyle factors including smoking, exercise and overall diet quality.) And in 2015, researchers in China, who examined the chilli consumption and health of nearly 500,000 Chinese adults, found that eating chillies was associated with lower risk of death. Those who consumed spicy foods almost every day had a 14% lower risk of death than those who ate spicy foods less than once a week.

One study found that those who consumed chillies almost every day had a lower risk of death (Credit: Getty Images)

“The major findings were that higher intake of spicy foods is related to a lower risk of mortality, particularly deaths due to cancer, heart disease, and respiratory diseases,” says researcher Lu Qi, professor of nutrition at Harvard’s school of public health.

This does not, however, mean that starting to eat large quantities of chilli peppers will protect your health – or protect you from respiratory illness – in the short-term.

It’s important to remember that the China study followed people for a median time of seven years each. So even if chillies had a protective effect on participants’ health, rather than the people who ate chillies happening to be healthier to begin with, the effect likely built up over time – not within weeks or months.

Qi tried to separate the effects of chilli consumption from everything else by controlling for age, sex, education level, marital status, diet and lifestyle factors including alcohol intake, smoking and physical activity. He says the lower risk of disease relating to eating chillies may be partly due to capsaicin.

“Certain ingredients in spicy foods, such as capsaicin, have been found to improve metabolic status, such as lipid profiles” – cholesterol in the blood – “and inflammation, and these may partly account for the observations in our study.”

Capsaicin, the main active ingredient in chillies, may improve blood cholesterol levels and inflammation (Credit: Getty Images)

A number of studies also have shown that capsaicin can increase the amount of energy we burn and can decrease our appetites.

Zumin Shi, associate professor at Qatar University’s human nutrition department, has found that chilli consumption is associated with lower risk of obesity and is beneficial for high blood pressure. So when she studied the effects of chilli pepper consumption on cognitive function, she expected a hat trick.

In one study, people who ate more chillies had poorer cognitive function

But when she measured Chinese adults’ cognitive function against their chilli consumption, she found that people who ate more chillies had poorer cognitive function. This effect was strongest with memory: chilli intake above 50g per day was associated with almost double the risk of self-reported poor memory. Still, it’s worth noting that self-reported data is widely considered unreliable.

The burning sensation that comes with eating chillies has long fascinated scientists. It also gives us some insight into why chillies may be associated with cognitive decline: the sensation is the result of plants evolving to protect themselves against diseases and pests.

“While some plants have evolved to become bitter or spicy to predators, it’s better if the plant can make themselves toxic, too,” says Kirsten Brandt, senior lecturer at the Human Nutrition Research Centre Population Health Sciences Institute at the UK’s Newcastle University.

But these compounds generally have a smaller effect on us than on insects. “A little bit of toxin can be good, such as caffeine, which speeds up our metabolism so we feel more awake,” she says. “However, a lot of it is bad for you.”

On the other hand, even if a compound within a certain spice may have beneficial effects, we normally don’t consume enough of it to make any difference.

Even if a compound within a spice like chilli has beneficial effects, we normally don’t consume enough of it to make a difference (Credit: Getty Images)

Take polyphenols: the compounds found in many plants that have anti-inflammatory effects. Spices’ health benefits are partly attributed to their high levels of these polyphenols. A 2014 review of research, however, says it’s still unclear whether the limited amount of these we get when we consume spices lessens their health benefits.

Curcumin “cure”

Another popular spice that is widely regarded to have beneficial effects on human health is turmeric. This is widely attributed to curcumin. A small molecule found in turmeric, it is commonly used in alternative medicine to treat inflammation, stress and many other conditions.

Robust evidence for turmeric being beneficial is lacking

Robust evidence for turmeric being beneficial, however, is lacking.

Numerous studies have found curcumin to have anti-cancer effects in the laboratory. But a lab environment is very different to the human body. And curcumin has poor water solubility, meaning the body can’t make proper use of it from the turmeric we consume.

In the Western world, this increasing interest in spices including turmeric as an alternative medicine was last seen in the Middle Ages, when spices were thought to have healing properties, says Paul Freedman, professor of history at Yale University.

In the West, the belief that spices like turmeric can help heal was last seen on a large scale in the Middle Ages (Credit: Getty images)

“Spices were used to balance the properties of food. People thought of food as having hot, cold, moist and dry qualities, and they needed balance,” says Freedman. Fish was considered cold and wet, for example, while spices were hot and dry.

The idea of using food as medicine, and of balancing out properties like hot and cold or wet and dry, also are main tenets of Ayurvedic medicine, which has been practised in India for thousands of years.

In the West, our modern fascination with spices brings us closer to a medieval outlook than 50 years ago – Paul Freedman

In many Western countries, where such ideas are much newer, “this idea of balance is shared with modern new-age medicine,” Freedman says. “Our modern fascination with spices brings us closer to a medieval outlook than 50 years ago – when there was a wall between modern medicine like antibiotics and superstitious medicine of the past that didn’t work.”

As part of her job, Kathryn Nelson, research assistant professor at the University of Minnesota’s Institute for Therapeutics Discovery and Development, looks at molecules to see if they could be a compound for new drug. She decided to study curcumin after she kept coming across the health claims associated with it.

“Researchers are able to exert effects in cells grown in test tubes by adding compounds to it and seeing what happens to the cells,” she says.

But she found that curcumin is a “terrible” drug molecule, as it isn’t bio-available – meaning the body can’t make use of it once it’s digested. It isn’t easily absorbed by the small intestine, and its structure can be modified when it binds with proteins in the small and large intestines. As a result, it doesn’t actually do much.

Because curcumin isn’t easily absorbed by the small intestine, it’s unlikely to provide much benefit after it’s eaten (Credit: Getty Images)

There could be something about turmeric that’s beneficial, but it’s not curcumin, she says. Plus, if turmeric is cooked as part of a meal, she says, it’s added alongside other foods, and heated up, so its chemical components change.

“There might be something else in turmeric worth looking at, but not curcumin, and it might not be one thing. It might need to be chemically modified or added to something to be beneficial.”

She says consuming lots of turmeric isn’t harmful, but she wouldn’t advise using it as self-medication.

Correlation vs causation

Chilli and turmeric have been widely studied, but most trials have only compared data on consumption and different health outcomes, which doesn’t separate cause from effect. And research done in labs doesn’t necessarily translate to the human body.

And as is true for so many nutritional studies, it’s difficult to tease out correlation versus causation.

Take the 2019 Italian study finding that there was a lower risk of death associated with chilli consumption. It was observational, so it’s impossible to know whether eating chilli made people live longer, whether already healthy people tend to consume more chilli, or if something else is at work.

One clue could, however, lie in how chillies are consumed by Italians and other Mediterranean cultures, says the study’s author Marialaura Bonaccio, epidemiologist at Italy’s Mediterranean Neurological Institute.

“Chilli is common in Mediterranean countries,” says Bonaccio. “It’s mostly eaten with pasta and legumes or vegetables.”

In the Mediterranean, chillies are often eaten with pasta and vegetables, or legumes, which may be the real reason behind any health benefit (Credit: Getty Images)

This is just one example of how spices could be indirectly beneficial – they’re eaten with legumes and vegetables.

Research also has found that adding a spice mix to burgers could potentially lead to fewer free radicals forming in a person’s body than those who ate the burger without spices, and could make the meat less carcinogenic. But these benefits could be explained simply by the preservative qualities of the spices, says Mellor, who wasn’t involved in the study.

“Putting spices into meat is a well-known technique to preserve meat,” he says. “The benefits of spices, therefore, may be more food preservation, rather than them having direct benefits to us. But either way, we could benefit as it still makes the food less harmful to us.”

Many researchers believe the health benefits of spices actually come from what we eat them with. For example, there’s a tendency to use them to replace salt, says Lipi Roy, clinical assistant professor at the NYU Langone Health medical centre in New York. “Spices make food delicious and flavourful, and they can be a healthier alternative to salt,” she says. (Read more about how much salt we really need).

Spices are often used instead of salt, which means their health benefits could come from lowering sodium, not from the spice itself (Credit: Getty Images)

We also tend to eat chillies with vegetables – which of course benefits our health, too.

So while golden lattes won’t do us any harm, we might be better off having some vegetables seasoned with a sprinkling of spices. And we certainly shouldn’t rely on them as a way to ward off – or to fight – any kind of illness.


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